Can I Stop Taking Clindamycin and Start the Doxycycline

Doxycycline vs. clindamycin: What's the departure?

• Doxycycline and clindamycin are antibiotics used to care for many unlike types of bacterial infections.
• Brand names for doxycycline include Vibramycin, Oracea, Adoxa, Atridox, Acticlate, Acticlate Cap, Doryx, Doxteric, Doxy, and Monodox.
• A brand name for clindamycin is Cleocin.
• Doxycycline and clindamycin are different types of antibiotics. Doxycycline is a tetracycline antibody and clindamycin is a lincosamide antibody.
• Side effects of doxycycline and clindamycin that are similar include nausea, vomiting, diarrhea, and tummy/abdominal pain.
• Side effects of doxycycline that are unlike from clindamycin include loose stools, molar discoloration if used in persons beneath viii years of age, and exaggerated sunburn.
• Side furnishings of clindamycin that are different from doxycycline include unpleasant/metallic taste in mouth, or hurting at the injection site, joint pain, vaginal itching or discharge, skin rash or itching, heartburn, sore throat, or changes in bowel habits (especially in older adults).

What are doxycycline and clindamycin?

Doxycycline is a tetracycline antibiotic used to treat many dissimilar types of infections, including respiratory tract infections due to Hemophilus influenzae, Streptococcus pneumoniae, or Mycoplasma pneumoniae. It too is used to treat nongonococcal urethritis (due to Ureaplasma), Rocky Mountain spotted fever, typhus, chancroid, cholera, brucellosis, anthrax, syphilis, acne, and periodontal disease.

Clindamycin is a lincosamide antibiotic used to treat a wide variety of bacterial infections. It works by stopping the growth of bacteria. Clindamycin may too be used before dental procedures in patients with sure center conditions (such as artificial eye valves) to help prevent serious infection of the centre (bacterial endocarditis).

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What are the side effects of doxycycline and clindamycin?

Doxycycline

Doxycycline is generally well tolerated. The most common side furnishings are:

• Diarrhea or loose stools
• Nausea
• Abdominal pain
• Vomiting

Tetracyclines, such every bit doxycycline, may cause tooth discoloration if used in persons below 8 years of age.

Exaggerated sunburn can occur with tetracyclines; therefore, minimize exposure to sunlight during handling.

Clindamycin

The most mutual side effects of clindamycin are

• Stomach pain
• Diarrhea

Clindamycin likewise oftentimes causes

• Nausea
• Vomiting
• Metallic taste
• Depression blood pressure level
• Rash
• Itching

Clindamycin causes Clostridium difficile-associated diarrhea (CDAD) because it can alter the normal bacteria in the colon and encourage overgrowth of Clostridium difficile, a bacteria which causes inflammation of the colon (pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting clindamycin (diarrhea, fever, intestinal pain, and maybe shock) should contact their doc immediately.

Other serious side furnishings of clindamycin include:

• Serious allergic reactions
• Blood disorders
• Stevens-Johnson syndrome
• Toxic epidermal necrolysis

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What is the dosage of doxycycline vs. clindamycin?

Doxycycline

• The absorption of doxycycline is not markedly afflicted by food; therefore, it can be taken with meals.
• For most infections, doxycycline is taken once or twice daily for 7 to 14 days.
• For adult infections, the usual dose of oral doxycycline is 200 mg on the first day of treatment (100 mg every 12 hours) followed by a dose of 100 to 200 mg/day as a single dose or divided and administered twice daily.

Clindamycin

• The recommended dose for adults for serious infections is 150 to 450 mg every 6 to 8 hours upwardly to a maximum dose of one.8 grams per day.
• For pediatric patients, the recommended dose is 8 to xx mg/kg/solar day divided into 3 or four equal doses.
• To avoid throat irritation, clindamycin should be taken with a total drinking glass of water.

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What drugs interact with doxycycline and clindamycin?

Doxycycline

• Do not have doxycycline at the aforementioned fourth dimension as aluminum-, magnesium-, or calcium-based antacids, such equally Mylanta, Maalox, Tums, or Rolaids because, like food, these medications bind doxycycline in the intestine and preclude its absorption. Similarly, practise non accept doxycycline with minerals (such every bit calcium or iron) or with bismuth subsalicylate (Pepto Bismol).
• Doxycycline may enhance the activity of warfarin (Jantoven, Coumadin) and cause excessive "thinning" of the blood leading to exaggerated bleeding, necessitating a reduction in the dose of warfarin. Phenytoin (Dilantin), carbamazepine (Tegretol), and barbiturates (such as phenobarbital) may enhance the metabolism (destruction) of doxycycline, thus making it less effective.
• Doxycycline may interfere with the activeness of penicillins and should not be combined with penicillins. Doxycycline may too reduce the upshot of oral contraceptives. Combining tetracycline and methoxyflurane (Penthrane) may reduce kidney function.

Clindamycin

• Clindamycin may act as a neuromuscular blocker. This means it can increase the action of neuromuscular blocking drugs (for example, pancuronium and vecuronium), which are used during surgery.

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Are doxycycline and clindamycin safe to use while significant or breastfeeding?

Doxycycline

• Tetracycline antibiotics, such as doxycycline, can have toxic effects on development of os in the fetus. Therefore, tetracyclines are not recommended during pregnancy unless there is no other advisable antibiotic.
• Doxycycline is secreted into breast milk, simply the extent of absorption past the breastfed infant is non known. Since tetracyclines tin can cause toxic furnishings on bone, the utilise of tetracyclines in nursing mothers is of concern. The doctor must decide whether to recommend that a nursing mother discontinue nursing during treatment with tetracyclines or alter to a different antibiotic.

Clindamycin

• The frequency of built abnormalities was not increased when pregnant women used clindamycin during the second and third trimesters. Clindamycin should not exist used during the kickoff trimester of pregnancy unless it is clearly needed, considering it has not been properly evaluated during the first trimester of pregnancy.
• Clindamycin is excreted in breast milk and should not be used by nursing mothers or nursing should be stopped.

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Related Illness Conditions

• 

  Pneumonia

  Pneumonia is inflammation of the lungs caused by fungi, bacteria, or viruses. Symptoms and signs include cough, fever, shortness of breath, and chills. Antibiotics treat pneumonia, and the choice of the antibiotic depends upon the cause of the infection.

• 

  Typhus

  Typhus is a disease caused past Rickettsia leaner. Symptoms and signs include fever, headache, nausea, vomiting, diarrhea, and rash. Antibiotics are recommended as the treatment for owned and epidemic typhus infections.

• 

  Cholera

  Cholera is an infectious disease characterized by intense vomiting and profuse watery diarrhea and that rapidly lease to dehydration and oftentimes death. Cholera is acquired by infection with the bacteria Vibrio cholerae, which may exist transmitted via infected fecal matter, nutrient, or water.

• 

  Endocarditis

  Endocarditis, a serious infection of one of the four middle valves is acquired past growth of bacteria on ane of the middle valves; leading to an infected massed chosen a "vegetation." The infection tin be caused by having leaner in the bloodstream after dental work, colonoscopy, or other similar procedures. Endocarditis symptoms include fever, fatigue, weakness, chills, aching muscles and joints, dark sweats, edema in the legs, feet, or abdomen, malaise, shortness of jiff and small peel lesions. Treatment for endocarditis is by and large aggressive antibiotic handling.

• 

  Streptococcal Infections

  Grouping A streptococcal infections are acquired by group A Streptococcus, a leaner that causes a variety of health issues, including strep throat, impetigo, cellulitis, erysipelas, and scarlet fever. There are more than than ten meg group A strep infections each year.

• 

  Clostridium Difficile Colitis (C. diff, C. difficle Colitis)

  Clostridium difficile (C. difficile) is a bacterium, and is one of the most mutual causes of infection of the colon. C. difficile spores are found ofttimes in hospitals, nursing homes, extended care facilities, and nurseries for newborn infants.

Treatment & Diagnosis

Medications & Supplements

Report Issues to the Nutrient and Drug Assistants

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References

FDA Prescribing Information

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